Antioxidative effects of sulfurous mineral water: protection against lipid and protein oxidation

Autori: S Benedetti 1F BenvenutiG NappiN A FortunatiL MarinoT AureliS De LucaS PagliaraniF Canestrari


  • 1Istituto di Istologia e Analisi di Laboratorio, Università di Urbino Carlo Bo, Urbino, Italy.

Titolo: Antioxidative effects of sulfurous mineral water: protection against lipid and protein oxidation


Objectives: To investigate the antioxidative properties of sulfurous drinking water after a standard hydropinic treatment (500 ml day(-1) for 2 weeks).

Subjects/methods: Forty apparently healthy adults, 18 men and 22 women, age 41-55 years old. The antioxidant profile and the oxidative condition were evaluated in healthy subjects supplemented for 2 weeks with (study group) or without (controls) sulfurous mineral water both before (T0) and after (T1) treatment.

Results: At T1, a significant decrease (P<0.05) in both lipid and protein oxidation products, namely malondialdehyde, carbonyls and AOPP, was found in plasma samples from subjects drinking sulfurous water with respect to controls. Concomitantly, a significant increment (P<0.05) of the total antioxidant capacity of plasma as well as of total plasmatic thiol levels was evidenced. Tocopherols, carotenoids and retinol remained almost unchanged before and after treatment in both groups.

Conclusions: The improved body redox status in healthy volunteers undergoing a cycle of hydropinic therapy suggests major benefits from sulfurous water consumption in reducing biomolecule oxidation, possibly furnishing valid protection against oxidative damage commonly associated with aging and age-related degenerative diseases.


Rivista: Randomized Controlled Trial

Categorie: Effetti Farmacologici